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The Human Body
Senses, sleep, and the machine that is you.
The Human Body is about the machine everyone is already operating — senses, sleep, reflexes, and the biology that turns out to be much stranger than most people assume.
Because every player owns the subject matter, the discussion tends to get personal fast and people start testing claims on themselves mid-round. It stays firmly on the science side rather than anything squeamish, so it is comfortable in a mixed room. Good for a table that likes arguing from experience.